Which regional route delivers chemotherapy into the peritoneal cavity?

Which regional route delivers chemotherapy into the peritoneal cavity?

• A. Intraarterial
• B. Intraperitoneal
• C. Intravesical
• D. Intrathecal

Answer: (B)

The main idea is delivering chemotherapy directly where the cancer cells are likely to be, by targeting a specific body compartment rather than going system-wide. Placing the drug into the peritoneal cavity creates very high concentrations at the peritoneal surfaces—where abdominal cancers often spread—while limiting immediate systemic exposure. This makes the intraperitoneal route especially effective for peritoneal carcinomatosis and ovarian cancer with abdominal implants, and it can be used with approaches like HIPEC to enhance tumor kill. In contrast, intraarterial administration targets tumors through their blood supply, intravesical delivery treats the bladder, and intrathecal delivery accesses the cerebrospinal fluid for CNS-related spread.

The main idea is delivering chemotherapy directly where the cancer cells are likely to be, by targeting a specific body compartment rather than going system-wide. Placing the drug into the peritoneal cavity creates very high concentrations at the peritoneal surfaces—where abdominal cancers often spread—while limiting immediate systemic exposure. This makes the intraperitoneal route especially effective for peritoneal carcinomatosis and ovarian cancer with abdominal implants, and it can be used with approaches like HIPEC to enhance tumor kill. In contrast, intraarterial administration targets tumors through their blood supply, intravesical delivery treats the bladder, and intrathecal delivery accesses the cerebrospinal fluid for CNS-related spread.