Which statement correctly differentiates neoadjuvant from adjuvant therapy?

Which statement correctly differentiates neoadjuvant from adjuvant therapy?

• A. Neoadjuvant is given before surgery to shrink tumors; adjuvant is given after surgery to eradicate residual disease
• B. Neoadjuvant is given after surgery to eradicate residual disease; adjuvant is given before surgery to shrink tumors
• C. Neoadjuvant is only used in metastatic disease; adjuvant only in early-stage
• D. Both are given before surgery

Answer: (A)